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→Postsynaptic Mechanisms of Chemical Transmission
* Ligand-gated channels may be completely insensitive to the voltage across the neuron's membrane. Other ligand-gated channels may also be gated by voltage.
* At the peak of the action synaptic potential, the membrane is in a steady state, and <math>I_{EPSP} + I_{L} = 0, </math> which allows us to determine the actual membrane voltage that will be reached by the nerve cell due to the synaptic input.
* From the channel equation, we know that <math>I_{EPSP} = g_{EPSP}(V - E_{EPSP})</math>, and <math>I_{L} = g_{L}(V - E_{L})</math>. Combining these equations, we can solve for the membrane voltage at the peak of the synaptic potential: <math display="block">
