Equilibrium Potentials II Answer 3

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Here are the answers for Figure 8, when sodium is permeable:

  • In the equilibrium condition, we computed that the internal sodium ion concentration was \left[\text{Na}^+\right]_\text{in} = 12\ \text{mM}, and we were given that its external concentration is \left[\text{Na}^+\right]_\text{out} = 120\ \text{mM}.
  • Using the Nernst equation, the predicted equilibrium potential for sodium across the membrane is {\displaystyle E_{\text{Na}^+} = 58\ \text{mV} \times \log_{10} \frac{120\ \text{mM}}{12\ \text{mM}} = +58\ \text{mV},} which is very different from the -81\ \text{mV} equilibrium potential that we calculated for the chloride and potassium ions.